Manchester Piccadilly to Milton Keynes Central Trains From £4.50*

Depart from Manchester Piccadilly and arrive at Milton Keynes Central in just around 1 hour and 40 minutes with a direct Avanti West Coast train – it’s a quick, reliable, and stress-free way to travel city to city.

Hop aboard your Manchester Piccadilly to Milton Keynes Central train and soak up tranquil views of rolling fields, wooded hills, and charming country villages as you glide through Staffordshire and Warwickshire into Buckinghamshire.

Avanti West Coast runs high-speed, long-distance services along the West Coast Main Line, connecting Manchester Piccadilly with Milton Keynes Central and major destinations such as London Euston, Liverpool, Birmingham, Glasgow and Edinburgh.

Departing from Manchester Piccadilly

With direct connections by tram, bus, and taxi, Manchester Piccadilly is just minutes from Piccadilly Gardens, the city’s main public transport hub, making it a convenient gateway from which to start your journey.

Located on Station Approach in the heart of the city, Manchester Piccadilly is one of the UK’s busiest and best-connected rail stations. And from here, you can travel all across the country with services from CrossCountry, Northern, Avanti West Coast and TransPennine Express, linking you directly to major destinations including Liverpool, the Lake District, London and the coast of North Wales.

Whether you’re headed north, south, east or west, Manchester Piccadilly offers fast, reliable connections all across the UK.

Main stops

Settle in and enjoy the ride aboard your Manchester to Milton Keynes train, as you pass through key stops like Wilmslow, Stafford and Rugby.

Arriving at Milton Keynes Central

Arriving into Milton Keynes Central, you’re just a 20-minute walk or a 10-minute bus ride away from all the shops, bars and restaurants of the centre: MK Retail Hub. 

Operated by London Northwestern Railway, the station offers step-free access, ticket machines, waiting rooms, and is easily reached by bus, taxi or on foot. A major hub for both Avanti West Coast and London Northwestern Railway services, Milton Keynes Central station provides regular high-speed trains to London Euston, Manchester, Liverpool, Birmingham and Glasgow, as well as regional connections to Bletchley, Northampton, Crewe and Stafford.

Alight in Milton Keynes and uncover a dynamic blend of culture, shopping and entertainment. Browse top brands at the centre: MK, or explore the city’s creative side at MK Gallery and the acclaimed Milton Keynes Theatre. Music fans can enjoy world-class jazz at The Stables or catch major live events at the legendary National Bowl. Home to wartime cryptography museum Bletchley Park, MK Dons FC, and the Open University, Milton Keynes is a city alive with innovation, history and cultural energy.

Avanti West Coast train classes 

• Standard: Enjoy a comfortable journey with free Wi-Fi, plug sockets at select seats, and the convenience of Click & Collect for food and drink from the onboard restaurant car.
• Standard Premium: Upgrade to Standard Premium for a more comfortable journey, with extra legroom, wider seats, a guaranteed table and plug sockets at every window seat.
• First Class: Travel in style from Manchester Piccadilly to Milton Keynes Central first class – with extra spacious seating, complimentary food and drink (including alcoholic options), at-seat service and access to exclusive first class lounges.

Avanti West Coast train travel advice

Get set for your Manchester Piccadilly to Milton Keynes Central train journey with everything you need to know before you go, including luggage info, travelling with children, bikes and pets, plus details on assisted travel.

• Luggage: Passengers can bring up to three items, such as suitcases, holdalls or backpacks, on board free of charge. Please use overhead racks, under-seat space and designated luggage areas and avoid blocking aisles or doors.
• Bicycles: Bikes and e-bikes are welcome on Avanti West Coast services, but require a free reservation. They are subject to availability, so it’s best to book early. Folding bikes are allowed on all services. E-scooters are not permitted on Avanti West Coast services.
• Children: Under-fives can travel for free on most routes. Children aged 5-15 are eligible for 50% off standard fares, while 16-17-year-olds can also access half-price tickets with a 16-17 Saver railcard.
• Pets: Passengers can bring up to two small pets on board free of charge. Dogs must be kept on a lead or in a secure carrier, and all pets must remain off seats.
• Passenger Assist: If you need a little extra help with boarding, carrying luggage, navigating stations or reserving a wheelchair space, you can request assistance from the Passenger Assist team. You can either book in advance when purchasing your ticket, through the app, or by speaking to staff at the station on the day.

*Information is subject to change. Please check the latest train timetable before your trip.